3-Methyl-2-nitroanisole → 2-Methoxy-6-methylaniline

HRID 1358939

Reaktionsgleichung

Reaktionsgleichung von HRID 1358939
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[N+:10]([O-])=O>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[NH2:10]

Komponenten

4

Edukt 1

HCID 792913-Methyl-2-nitroanisole

Produkt 1

HCID 4592492-Methoxy-6-methylaniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 1-methoxy-3-methyl-2-nitrobenzene (15.04 g, 0.09 mol) in ethanol (250 ml) was hydrogenated over 10% palladium on charcoal (4 g) at atmospheric pressure and at room temperature, for 18 h. The catalyst was removed by filtration, and the filtrate evaporated under reduced pressure to leave the title compound (D28) as an amber oil, which crystallised on standing (11.18 g, 91%).

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. customthe filtrate evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-6d7e7e529731450082821b906b6e9160
Quelldatensatz
uspto-grants-2003_07
Patentnummer
US06599904B2

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