HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → Ethyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | p-Chlorophenyl dichlorophosphate | HCID 69879 | — |
| Edukt | L-Alanine, ethyl ester, hydrochloride (1:1) | HCID 2724356 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Ethyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate | HCID 44226153 | — |
Reaktionsschritte
Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.090 M) of 4-chlorophenyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1:1* mixture of diastereoisomers.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07879815B2 |
| Quelldatensatz | uspto-grants-2011_02 |
| ORD ID | ord-3ddd7d4e011440eb9d7c77cc15a78b39 |
| Quellennotiz | uspto-grants-2011_02 |