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HRID1359935

反应详情

EQUATION

反应方程式

HRID 1359935 的结构方程式

REACTANTS

反应物

3
结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：O=P(Cl)(Cl)Oc1ccc(Cl)cc1
HCID69879

p-Chlorophenyl dichlorophosphate

C6H4Cl3O2P

结构：CCOC(=O)[C@H](C)N.Cl
HCID2724356

(S)-Ethyl 2-aminopropanoate hydrochloride

C5H12ClNO2

PRODUCTS

生成物

1
结构：CCOC(=O)[C@H](C)NP(=O)(Cl)Oc1ccc(Cl)cc1
HCID44226153

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.090 M) of 4-chlorophenyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1:1* mixture of diastereoisomers.