HCID 21070649, Verbindung → HCID 21070647, Verbindung

HRID 1371766Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1371766
[N:1]([CH:4]1[CH2:9][CH2:8][N:7]([S:10]([CH3:13])(=[O:12])=[O:11])[CH2:6][CH:5]1[OH:14])=[N+]=[N-]>C(O)C.[Pd]>[NH2:1][CH:4]1[CH2:9][CH2:8][N:7]([S:10]([CH3:13])(=[O:12])=[O:11])[CH2:6][CH:5]1[OH:14]

Komponenten

4

Edukt 1

HCID 21070649HCID 21070649, Verbindung

Produkt 1

HCID 21070647HCID 21070647, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

The azide (300 mg, 1.36 mmol, Example 304) was dissolved in ethanol and hydrogenated at 45 psi under the catalyst of 10% palladium on carbon (30 mg) for 1 hour. The mixture was filtered and the filtrate was concentrated to give a white solid. 245 mg, 93%. The compound was used directly for the next step.

Aufarbeitung

  1. filtrationThe mixture was filtered
  2. concentrationthe filtrate was concentrated
  3. customto give a white solid

Quellen und Nachweise

ORD-Eintrag
ord-092c585777ee448096f9adf9fe732cb3
Quelldatensatz
uspto-grants-2007_01
Patentnummer
US07157455B2

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