Water → N-[2-(dimethylamino)ethyl]benzenesulfonamide

HRID 1373120Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1373120
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].C(N(CC)CC)C.[C:14]1([S:20](Cl)(=[O:22])=[O:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.O>ClCCl>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH:5][S:20]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:22])=[O:21]

Komponenten

6

Edukt 4

HCID 962WaterHCID 7369Benzenesulfonyl chlorideHCID 8471TriethylamineHCID 66053N,N-Dimethylethylenediamine

Produkt 1

HCID 2478570N-[2-(dimethylamino)ethyl]benzenesulfonamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

2.8 g (30 mmol) of N,N-dimethylethylenediamine are placed in 100 ml of dichloromethane and 8.3 ml (60 mmol) of triethylamine. While cooling with ice a solution of 3.9 ml (30 mmol) of benzenesulphonic acid chloride in 100 ml of dichloromethane is added dropwise and the mixture is stirred overnight at ambient temperature. Water is added and the mixture is extracted with dichloromethane. The organic phase is dried and evaporated down.

Aufarbeitung

  1. additionis added dropwise
  2. extractionthe mixture is extracted with dichloromethane
  3. customThe organic phase is dried
  4. customevaporated down

Quellen und Nachweise

ORD-Eintrag
ord-9340ad6b2c154970a0176672e48eda37
Quelldatensatz
uspto-grants-2007_01
Patentnummer
US07160901B2

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