4-Fluorobenzylic alcohol → 4-Fluorobenzoic Acid
Reaktionsgleichung
Br([O-])(=O)=[O:2].[Na+].[F:6][C:7]1[CH:14]=[CH:13][C:10]([CH2:11][OH:12])=[CH:9][CH:8]=1>C(#N)C.O>[F:6][C:7]1[CH:14]=[CH:13][C:10]([C:11]([OH:2])=[O:12])=[CH:9][CH:8]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The separated catalyst was added to a fresh batch of sodium bromate (0.3 g) and 4-fluorobenzyl alcohol (0.256 g, 2 mmol) in acetonitrile:water (1:1, 10 ml). The above procedure was repeated to give 4-fluorobenzoic acid as a white solid (0.25 g, 88%).
Quellen und Nachweise
- ORD-Eintrag
- ord-3613e9979b044dd4a9ed5815f48c5a94
- Quelldatensatz
- uspto-grants-2010_06
- Patentnummer
- US07728159B2
Notizen zur Reaktion
Wird geladen…