HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
[Methyl-(toluene-4-sulfonyl)-amino]-acetic acid → N-(toluene-4-sulfonyl)sarcosyl-beta-(3-pyridyl)alanine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | [Methyl-(toluene-4-sulfonyl)-amino]-acetic acid | HCID 802555 | — |
| Edukt | H-Ala(3-pyridyl)-OMe.2HCl | HCID 46862166 | — |
| Produkt | N-(toluene-4-sulfonyl)sarcosyl-beta-(3-pyridyl)alanine | HCID 20582824 | 17% |
Reaktionsschritte
N-(Toluene-4-sulfonyl)sarcosine was coupled to 3-(3-pyridyl)alanine methyl ester dihydrochloride using the procedure described in Method 3 to give N-(toluene-4-sulfonyl)sarcosyl-β-(3-pyridyl)alanine (166 mg, 17%). The title compound was prepared via hydrolysis of the methyl ester using 1N aqueous NaOH in dioxane/water (129 mg, 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07166580B2 |
| Quelldatensatz | uspto-grants-2007_01 |
| ORD ID | ord-01c09ea1fc624e848211ad1dc4ed17dc |
| Quellennotiz | uspto-grants-2007_01 |