1-(p-Methoxyphenyl)-2-propanone → 4-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one

HRID 1380507Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1380507
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](=[O:12])[CH3:11])=[CH:5][CH:4]=1.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH3:18])[CH:17]=[C:9]([C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[C:10](=[O:12])[CH3:11]

Komponenten

3

Edukt 2

HCID 312311-(p-Methoxyphenyl)-2-propanoneHCID 78373Dimethylformamide dimethyl acetal

Produkt 1

HCID 539901024-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one

Versuchsvorschrift

35 g of 3-(4-methoxyphenyl)-2-propanone and 70 ml of dimethylformamide dimethyl acetal are heated at 70° C. for 3 hours. The reaction mixture is then evaporated to dryness in vacuo, and the residue is induced to crystallise with petroleum ether and the crystals are filtered off with suction. 43 g of 4-dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one are obtained. Melting point 51° C.

Aufarbeitung

  1. customThe reaction mixture is then evaporated to dryness in vacuo
  2. customto crystallise with petroleum ether
  3. filtrationthe crystals are filtered off with suction

Quellen und Nachweise

ORD-Eintrag
ord-d23d5eee193847b28a610448a6f07df4
Quelldatensatz
uspto-grants-1986_04
Patentnummer
US04582834

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