Styrene → HCID 21273965, Verbindung

HRID 1383049Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1383049
[CH3:1][C:2]1[NH:3][C:4](C)=[C:5]([C:18]([O:20][CH3:21])=[O:19])[CH:6]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:7]=1[C:8]([O:10][CH3:11])=[O:9].[CH2:23]=[CH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1.B(F)(F)F.CCOCC>C(Cl)(Cl)Cl>[CH3:1][C:2]12[CH2:23][CH:24]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:5]([C:18]([O:20][CH3:21])=[O:19])([CH:6]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:7]1[C:8]([O:10][CH3:11])=[O:9])[CH:4]=[N:3]2

Komponenten

5

Edukt 3

HCID 7501StyreneHCID 8000Boron trifluoride etherateHCID 129839Dimethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

Produkt 1

HCID 21273965HCID 21273965, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

To 0.45 g (1.5 mmol) dimethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate (1) in 25 ml CHCl3 under N2 and cooled to 0°-10° in an ice bath there was added 3.12 g (30.0 mmol) of commercially obtained styrene (4) followed by 0.64 g (4.5 mmol) boron trifluoride etherate added dropwise via syringe. The resulting solution was stirred at 0°-10° for 3 hours and then at room temperature for 16 hours.

Aufarbeitung

  1. additionadded dropwise via syringe
  2. waitat room temperature for 16 hours

Quellen und Nachweise

ORD-Eintrag
ord-0402dd5bde8348beae73b0fc92d99913
Quelldatensatz
uspto-grants-1989_02
Patentnummer
US04808718

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