[F:1][C:2]1[CH:7]=[C:6]([O:8]C(=O)C)[CH:5]=[CH:4][C:3]=1[C:12]([O:14][CH2:15][CH:16]([CH2:19][CH3:20])[CH2:17][CH3:18])=[O:13].C(N)C1C=CC=CC=1>C(O)C.CCOCC>[F:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:12]([O:14][CH2:15][CH:16]([CH2:19][CH3:20])[CH2:17][CH3:18])=[O:13]9.3 Grams (0.036 mol) of the compound prepared in the above (1) was dissolved in 250 ml of ethanol, and 7.7 g (0.0772 mol) of benzylamine was dropwise added. Further, the mixture was stirred at room temperature for 1 day, then diluted with 300 ml of ether, consecutively washed with diluted hydrochloric acid and with water, and dried over magnesium sulfate. The solvent was distilled off, and the residue was purified for isolation with a silica gel column chromatograph to give an end product in the yield of 95%.
Wird geladen…
