Acetic Anhydride → Ethyl 1-ethyl-3-pyrrolecarboxylate

HRID 1384078

Reaktionsgleichung

Reaktionsgleichung von HRID 1384078
[CH:1]([N:3]([CH2:5][C:6](O)=O)[CH3:4])=O.[C:9]([O:13][CH2:14][CH3:15])(=[O:12])[C:10]#[CH:11].C(OC(=O)C)(=O)C>>[CH2:5]([N:3]1[CH:1]=[CH:11][C:10]([C:9]([O:13][CH2:14][CH3:15])=[O:12])=[CH:4]1)[CH3:6]

Komponenten

4

Edukt 3

HCID 7918Acetic AnhydrideHCID 12182Ethyl propiolateHCID 11789184N-formylsarcosine

Produkt 1

HCID 22738058Ethyl 1-ethyl-3-pyrrolecarboxylateAusbeute 71,3 %

Versuchsvorschrift

Using 117.1 g (1 mol) of N-formylsarcosine, 98.1 g (1 mol) of ethyl propiolate and 638 ml of acetic anhydride, a reaction and post treatment were conducted in a similar manner as in Referential Example 1. The resulting brown oil was distilled under reduced pressure and a 103-104° C. fraction was collected under 4 mmHg, whereby 109.19 g of the title compound were obtained (yield: 71.3%).

Aufarbeitung

  1. customa reaction and post treatment
  2. distillationThe resulting brown oil was distilled under reduced pressure and a 103-104° C. fraction
  3. customwas collected under 4 mmHg

Quellen und Nachweise

ORD-Eintrag
ord-4b6c21a5640e439d8cd5ef137a74dabf
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06258805B1

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