Aluminum isopropoxide → 3-(3-Isopropylphenyl)butanol

HRID 1384408Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1384408
CC(C)[O-].[Al+3].CC(C)[O-].CC(C)[O-].[CH:14]([C:17]1[CH:18]=[C:19]([CH:23]([CH3:27])[CH2:24][CH:25]=[O:26])[CH:20]=[CH:21][CH:22]=1)([CH3:16])[CH3:15]>C(O)(C)C.CCOCC>[CH:14]([C:17]1[CH:18]=[C:19]([CH:23]([CH3:27])[CH2:24][CH2:25][OH:26])[CH:20]=[CH:21][CH:22]=1)([CH3:16])[CH3:15]

Komponenten

5

Edukt 2

HCID 11143Aluminum isopropoxideHCID 86209Florhydral

Produkt 1

HCID 220355223-(3-Isopropylphenyl)butanolAusbeute 73,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 3776IsopropanolLösungsmittel2×

Versuchsvorschrift

To a refluxing solution of 132.8 g aluminum isopropoxide in 800 ml of isopropanol, a solution of 300 g of 3-(3-isopropylphenyl)butanal in 200 ml of isopropanol was dropped in. The resulting solution was refluxed for 1.5 hours, then cooled and diluted with ether. Then, the organic phase was washed with brine, dried, and evaporated to dryness. The resulting oil was distilled to yield 223.5 g of a colorless oil.

Aufarbeitung

  1. temperatureThe resulting solution was refluxed for 1.5 hours
  2. temperaturecooled
  3. washThen, the organic phase was washed with brine
  4. customdried
  5. customevaporated to dryness
  6. distillationThe resulting oil was distilled

Quellen und Nachweise

ORD-Eintrag
ord-50b35a20e7ae42c9a03a95b57838f8f4
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06258854B1

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