Dichloromethane → 6-[(3-{[Tert-butyl(dimethyl)silyl]oxy}propyl)amino]-2-chloro-5-fluoronicotinonitrile
Reaktionsgleichung
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[Cl:8].[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[CH3:45][N:46]([c:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1)[CH3:53].[Cl:24][c:25]1[n:26][c:27]([Cl:28])[c:29]([F:30])[cH:31][c:32]1[C:33]#[N:34].[Cl:42][CH2:43][Cl:44].[Cl:9][c:10]1[c:11]([C:12]#[N:13])[cH:14][c:15]([F:23])[c:16]([NH:18][CH2:19][CH2:20][CH2:21][OH:22])[n:17]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:22][CH2:21][CH2:20][CH2:19][NH:18][c:16]1[c:15]([F:23])[cH:14][c:11]([C:12]#[N:13])[c:10]([Cl:9])[n:17]1
