(1,1'-Biphenyl)-3-ol, 4-nitro- → 2-Amino-5-phenylphenol

HRID 1385380Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1385380
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][C:5]=1[OH:16])([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][C:5]=1[OH:16]

Komponenten

4

Edukt 1

HCID 87437(1,1'-Biphenyl)-3-ol, 4-nitro-

Produkt 1

HCID 203762-Amino-5-phenylphenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 2-nitro 5-phenyl phenol (1.2 g, 5.5 mmol) in methanol was treated with 10% Pd/C (1.2 g). The reaction mixture was flushed with hydrogen and allowed to stir overnight. The reaction mixture was filtered through celite and the filtrate was concentrated in vacuo to afford desired (1.01 g, 98%). EI-MS m/z 186 (M+H)+

Aufarbeitung

  1. customThe reaction mixture was flushed with hydrogen
  2. filtrationThe reaction mixture was filtered through celite
  3. concentrationthe filtrate was concentrated in vacuo
  4. customto afford

Quellen und Nachweise

ORD-Eintrag
ord-3b82b58ae9034a208443b76ab0f0a2c8
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06262113B1

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