Acetic Anhydride → Isoxazolo(3,4-d)pyrimidine-4,6(5H,7H)-dione, 3,5,7-trimethyl-
Reaktionsgleichung
[CH3:1][N:2]1[C:9]([NH:10][OH:11])=[CH:8][C:6](=[O:7])[N:5]([CH3:12])[C:3]1=[O:4].[C:13](OC(=O)C)(=O)[CH3:14]>>[CH3:13][C:14]1[O:11][N:10]=[C:9]2[C:8]=1[C:6](=[O:7])[N:5]([CH3:12])[C:3](=[O:4])[N:2]2[CH3:1]Komponenten
3
Versuchsvorschrift
One gram of 1,3-dimethyl-6-hydroxyaminouracil is boiled with 10 ml of acetic anhydride at 140° C. for 1 hour and, when hot, the insolubles are filtered off. The filtrate is concentrated to dryness to recover 0.7 g of the captioned compound as colorless needles. As recrystallized from ethanol, the compound melts at 200°-202° C.
Aufarbeitung
- filtrationwhen hot, the insolubles are filtered off
- concentrationThe filtrate is concentrated to dryness
- customto recover 0.7 g of the captioned compound as colorless needles
- customAs recrystallized from ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-4746a670d1ac4fb7b53acd69ce45ad6f
- Quelldatensatz
- uspto-grants-1980_05
- Patentnummer
- US04202975
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