Water → tert-butyl (+/-)-4-(4-(5-(tert-butoxycarbonylamino)-2-(2,6-difluorophenyl)thiazole-4-carboxamido)-1-methyl-1H-pyrazol-5-yl)-2-methylpiperazine-1-carboxylate
Reaktionsgleichung
[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27](=[O:28])[NH:29][c:30]1[c:31]([C:43](=[O:44])[OH:45])[n:32][c:33](-[c:35]2[c:36]([F:42])[cH:37][cH:38][cH:39][c:40]2[F:41])[s:34]1.[NH2:1][c:2]1[cH:3][n:4][n:5]([CH3:21])[c:6]1[N:7]1[CH2:8][CH:9]([CH3:20])[N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]1.[O:71]=[CH:72][N:73]([CH3:74])[CH3:75].[OH2:70].[P-:46]([F:47])([F:48])([F:49])([F:50])([F:51])[F:52].[n:53]1([O:54][C:55]([N:56]([CH3:57])[CH3:58])=[N+:59]([CH3:60])[CH3:61])[c:62]2[n:63][cH:64][cH:65][cH:66][c:67]2[n:68][n:69]1>>[NH:1]([c:2]1[cH:3][n:4][n:5]([CH3:21])[c:6]1[N:7]1[CH2:8][CH:9]([CH3:20])[N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]1)[C:43]([c:31]1[c:30]([NH:29][C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:28])[s:34][c:33](-[c:35]2[c:36]([F:42])[cH:37][cH:38][cH:39][c:40]2[F:41])[n:32]1)=[O:44]
