Tetrahydrofuran → HCID 53867664, Verbindung

HRID 1414090

Reaktionsgleichung

Reaktionsgleichung von HRID 1414090
[S:1](Cl)(Cl)(=[O:3])=[O:2].[NH:6]([C:8]1[CH:17]=[CH:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[N:9]=1)[NH2:7].C(N([CH2:23][CH3:24])CC)C.O1[CH2:29][CH2:28][CH2:27][CH2:26]1>>[CH2:26]([N:7]([S:1]([C:24]1[CH:23]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:3])=[O:2])[NH:6][C:8]1[CH:17]=[CH:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[N:9]=1)[CH2:27][CH2:28][CH2:29][CH2:26][CH2:27][CH2:28][CH2:29][CH2:14][CH2:15][CH2:16][CH3:17]

Komponenten

5

Edukt 4

HCID 8028Tetrahydrofuran2×HCID 8471TriethylamineHCID 24648Sulfuryl chlorideHCID 85111Quinoline, 2-hydrazinyl-

Produkt 1

HCID 53867664HCID 53867664, Verbindung

Versuchsvorschrift

To a solution of the sulfonyl chloride in 10 ml tetrahydrofuran was added a solution of the hydrazinoquinoline and triethylamine in 30 ml tetrahydrofuran (4 ml dimethylformamide was included to aid solubility). The temperature of the reaction mixture was maintained below 10° C. during the addition and for 30 minutes thereafter while the mixture was continuously stirred. The product was recovered as in Example 1 yielding 8.4 g of a tan solid. NMR and IR analysis confirmed the product to be 2-(dodecylbenzenesulfonylhydrazino)quinoline.

Aufarbeitung

  1. temperatureThe temperature of the reaction mixture was maintained below 10° C. during the addition and for 30 minutes
  2. customThe product was recovered as in Example 1 yielding 8.4 g of a tan solid

Quellen und Nachweise

ORD-Eintrag
ord-41a88024ab7e41cb80ab666e8ac9a35a
Quelldatensatz
uspto-grants-1981_02
Patentnummer
US04252959

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