Isopropylamine → HCID 21487924, Verbindung

HRID 1414620Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1414620
[C:1]([C:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[O:11][C:10]=1[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH:26]2[O:28][CH2:27]2)=[CH:20][CH:19]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:29]([NH2:32])([CH3:31])[CH3:30]>>[C:1]([C:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[O:11][C:10]=1[C:18]1[CH:19]=[CH:20][C:21]([O:24][CH2:25][CH:26]([OH:28])[CH2:27][NH:32][CH:29]([CH3:31])[CH3:30])=[CH:22][CH:23]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 6363IsopropylamineHCID 21487960HCID 21487960, Verbindung

Produkt 1

HCID 21487924HCID 21487924, Verbindung

Versuchsvorschrift

3-Benzoyl-2-[4'-(2,3-epoxypropoxy)phenyl]benzofuran (1.9 g., 5.2 mmol.) was dissolved in 30 ml. of freshly distilled isopropylamine and the mixture was heated in a stainless steel pressure bomb at 100° for 4.5 hours. The contents of the bomb were concentrated under reduced pressure to give the title compound. The title compound was dissolved in ether and an ethereal solution of hydrochloric acid was added to precipitate the corresponding hydrochloride salt, m.p. 53°-59°.

Aufarbeitung

  1. concentrationThe contents of the bomb were concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a6c6f7ef136d48d593f4261aab6050bf
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04001426

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