Hydrochloric Acid → HCID 54523957, Verbindung

HRID 1415217Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415217
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[OH:11][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=O)=[CH:14][C:13]=1[O:20][CH3:21].N1CCOCC1.Cl>CS(C)=O>[OH:11][C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[CH:2][C:1]([CH:4]2[C:8](=[O:9])[CH2:7][CH2:6][C:5]2=[O:10])=[O:3])=[CH:14][C:13]=1[O:20][CH3:21]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 1183VanillinHCID 8083MorpholineHCID 3364732-Acetyl-1,3-cyclopentanedione

Produkt 1

HCID 54523957HCID 54523957, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 679Dimethyl SulfoxideLösungsmittel

Versuchsvorschrift

2-Acetyl-1,3-cyclopentanedione (3.03 g.) was treated with 4-hydroxy-3-methoxybenzaldehyde (5.05 g.) in 50 ml. of dimethylsulfoxide at 80° C for 13 minutes in the presence of 4 ml. of morpholine. After cooling, 80 ml. of 1 N hydrochloric acid was added to the reaction mixture, depositing a crystalline product. The solid was collected by filtration, and washed with water and ethanol successively, and it was then dried. The Claiseu-Schmidt condensation product, 2-(4-hydroxy-3-methoxycinnamoyl)-1,3-cyclopentanedione, (1.3 g.) was obtained in an orange crystalline form, which showed mp. 274°- 275° C after recrystallization from dioxane.

Aufarbeitung

  1. temperatureAfter cooling
  2. filtrationThe solid was collected by filtration
  3. washwashed with water and ethanol successively
  4. customit was then dried

Quellen und Nachweise

ORD-Eintrag
ord-bb11280a56ac4ea09b75dd2526e6d08f
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04003936

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