Hydrogen Bromide → 3-Phenoxyphenol

HRID 1416949

Reaktionsgleichung

Reaktionsgleichung von HRID 1416949
[O:1]([C:8]1[CH:9]=[C:10]([O:14]C)[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br>C(O)(=O)C>[O:1]([C:8]1[CH:9]=[C:10]([OH:14])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 2

HCID 260Hydrogen BromideHCID 742521-Methoxy-3-phenoxybenzene

Produkt 1

HCID 128423-Phenoxyphenol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

3-Phenoxyanisole (8.3 g) was added to a mixture of 50 mL of 40% HBr and 100 mL of glacial acetic acid. The resultant mixture was heated under reflux for 48 hours, then cooled and concentrated under reduced pressure. The residue was taken up in EtOAc, washed with water, saturated NaHCO3, and brine. After drying with MgSO4, and concentration under reduced pressure, 3-phenoxyphenol was obtained and used without further purification.

Aufarbeitung

  1. temperatureunder reflux for 48 hours
  2. temperaturecooled
  3. concentrationconcentrated under reduced pressure
  4. washwashed with water, saturated NaHCO3, and brine
  5. dry with materialAfter drying with MgSO4, and concentration under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-f89d7d897c4d4a39a8c7436c257186e9
Quelldatensatz
uspto-grants-1999_06
Patentnummer
US05916922

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