1-Propanol → HCID 131720992, Verbindung

HRID 1418799Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1418799
[O:1]=[C:2]([C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH3:14])=[CH:8][CH:7]=1)[C:3]([OH:5])=[O:4].O.[C:16]1(C)[CH:21]=CC(S(O)(=O)=O)=C[CH:17]=1.C1(C)C=CC=CC=1.CCCO>O>[CH2:17]([O:4][C:3](=[O:5])[C:2]([C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH3:14])=[CH:8][CH:7]=1)=[O:1])[CH2:16][CH3:21]

Komponenten

6

Edukt 4

HCID 10311-PropanolHCID 1140TolueneHCID 521998p-Toluenesulfonic acid monohydrateHCID 50548412-(4-Ethoxyphenyl)-2-oxoacetic acid

Produkt 1

HCID 131720992HCID 131720992, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

10.4 g (50 mmol) of α-oxo-4-ethoxyphenylacetic acid (Bandyopahyay et al., J. Ind. Chem. Soc. 66(4), 239, 1989) and 1.0 g of p-toluenesulfonic acid-monohydrate are refluxed into a mixture of 100 ml of toluene and 50 ml of N-propanol while in a water separator until no more water separates out. Then, it is concentrated by evaporation in a vacuum, the residue is dispersed between ethyl acetate and sodium bicarbonate solution, the organic phase is dried on magnesium sulfate, filtered and concentrated by evaporation.

Aufarbeitung

  1. concentrationThen, it is concentrated by evaporation in a vacuum
  2. additionthe residue is dispersed between ethyl acetate and sodium bicarbonate solution
  3. customthe organic phase is dried on magnesium sulfate
  4. filtrationfiltered
  5. concentrationconcentrated by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-4fb444f1d22d4e30bd56431180d64251
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05885548

Notizen zur Reaktion

Wird geladen…