2-Bromophenyl isocyanate → sb 225002

HRID 1419361Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1419361
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:20]([NH:19][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[Br:12])=[O:21]

Komponenten

3

Edukt 2

HCID 1370972-Bromophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Produkt 1

HCID 3854666sb 225002Ausbeute 47 %

Versuchsvorschrift

N-(2-Hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-bromophenyl isocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound(530 mg, 47%). EI-MS m/z 350(M-H)-

Aufarbeitung

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

Quellen und Nachweise

ORD-Eintrag
ord-a74109b5311d41f88d24d3a9f847716a
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05886044

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