Benzyl Bromide → HCID 69471538, Verbindung

HRID 1420132Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1420132
[F:1][CH2:2][C:3]([NH2:5])=[S:4].[CH2:6]([Br:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(Cl)(Cl)Cl.CCOCC>[BrH:13].[CH2:6]([S:4][C:3](=[NH:5])[CH2:2][F:1])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Komponenten

5

Edukt 2

HCID 7498Benzyl BromideHCID 167372062-Fluorothioacetamide

Produkt 1

HCID 69471538HCID 69471538, VerbindungAusbeute 54 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 6212ChloroformLösungsmittel

Versuchsvorschrift

Fluorothioacetamide (3.39 g) and benzyl bromide (6.23 g) were refluxed in chloroform (40 ml), under nitrogen, for 16 h. After cooling, the mixture was diluted with ether (200 ml) and the resulting orange solid filtered off. The solid was washed with more ether and dried over P2O5 in vacuo to give 5.19 g of the desired product.

Aufarbeitung

  1. temperatureAfter cooling
  2. filtrationthe resulting orange solid filtered off
  3. washThe solid was washed with more ether
  4. dry with materialdried over P2O5 in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-93a754e113f9425abbc9ad40dd8b8ff7
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05889056

Notizen zur Reaktion

Wird geladen…