HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → (S)-2-acetylthio-3-phenylpropanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | (2S,3S)-oxirane-2,3-dicarboxylic acid | HCID 6454714 | — |
| Edukt | (R)-2-Bromo-3-phenylpropionic acid | HCID 11746403 | — |
| Edukt | HCID 178477231 | HCID 178477231 | — |
| Produkt | (S)-2-acetylthio-3-phenylpropanoic acid | HCID 10176891 | 75% |
Reaktionsschritte
In the just cited patent application EP-0 524 553 (R)-2-bromo-3-phenyl-propionic acid is reacted, under nitrogen, with thioacetic acid/potassium carbonate in the presence of 1M sodium hydroxide to give (S)-2-acetylthio-3-phenyl-propionic acid which is extracted in ethyl acetate with a yield of 75%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06080881 |
| Quelldatensatz | uspto-grants-2000_06 |
| ORD ID | ord-9f7f0bb625724013b05bbd3c23d2f7d2 |
| Quellennotiz | uspto-grants-2000_06 |