HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → Temozolomide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | Acetonitrile | HCID 6342 | — |
| Edukt | Temozolomide hydrochloride | HCID 11658676 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Temozolomide | HCID 5394 | — |
Reaktionsschritte
According to the present invention, the dissolution of Temozolomide hydrochloride in the mixture of acetic acid, acetonitrile, and water is complete (at pH range of 3-4), results in the precipitation of Temozolomide upon cooling.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07612202B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-73fd4603a2d447539955f29b9ce3c3ea |
| Quellennotiz | uspto-grants-2009_11 |