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HRID1433126

反应详情

EQUATION

反应方程式

HRID 1433126 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：CC#N
HCID6342

Acetonitrile

C2H3N

结构：Cl.Cn1nnc2c(C(N)=O)ncn2c1=O
HCID11658676

未命名化合物

PRODUCTS

生成物

1
结构：Cn1nnc2c(C(N)=O)ncn2c1=O
HCID5394

Temozolomide

C6H6N6O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

According to the present invention, the dissolution of Temozolomide hydrochloride in the mixture of acetic acid, acetonitrile, and water is complete (at pH range of 3-4), results in the precipitation of Temozolomide upon cooling.