1-Methylimidazole → HCID 67047038, Verbindung

HRID 1438377Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1438377
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[CH3:11])=[CH:6][CH:5]=1)=[CH2:3].CN1C=CN=C1.[N+](=[CH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[N-]>C1(C)C=CC=CC=1>[C:10]([C:7]1[CH:8]=[CH:9][C:4]([C:2]2([CH3:3])[CH2:1][CH:21]2[C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:5][CH:6]=1)(=[O:12])[CH3:11]

Komponenten

5

Edukt 3

HCID 13901-MethylimidazoleHCID 12192Ethyl diazoacetateHCID 589438p-Isopropenylacetophenone

Produkt 1

HCID 67047038HCID 67047038, VerbindungAusbeute 22 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a stirred solution of 1-[4-(1-methylethenyl)phenyl]ethanone (711 mg, 4.44 mmol, trans) (Org. Lett., 2002, 4(1), 107-109), N-methylimidazole (1.06 ml, 13.3 mmol) and Co(TPP)(89 mg, 0.13 mmol) in toluene (10 ml) was added ethyl diazoacetate (0.65 ml, 6.21 mmol) in one portion at ambient temperature. The same procedure as described in Example 2H was performed to give the title compound (236 mg, 22%) as dark yellow oil.

Quellen und Nachweise

ORD-Eintrag
ord-7796ae0273e245e8be2c30502ab330d1
Quelldatensatz
uspto-grants-2009_11
Patentnummer
US07622589B2

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