Citric Acid → HCID 13785667, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([O:11]S(C=C)(=O)=O)=[C:4]([CH3:17])[CH:3]=1.C(=O)([O-])[O-].[K+].[K+].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O.C(O)C>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([OH:11])=[C:4]([CH3:17])[CH:3]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of compound 106 (27.8 g, 100 mmol) and potassium carbonate (27.6 g, 200 mmol) in ethanol water 1/1 (600 ml) was refluxed for one hour. Citric acid (5%) was added and the mixture was extracted three times with DCM. The organic phase was dried with sodium sulphate and evaporated under reduced pressure which gave the title compound (19 g, 100%).
Aufarbeitung
- extractionthe mixture was extracted three times with DCM
- dry with materialThe organic phase was dried with sodium sulphate
- customevaporated under reduced pressure which
Quellen und Nachweise
- ORD-Eintrag
- ord-0554f642280a486ab7d1c16edd532465
- Quelldatensatz
- uspto-grants-2010_02
- Patentnummer
- US07659245B2
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