Water → N-Chloro-4-methoxybenzamide

HRID 1450640Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1450640
[CH3:1][O:2][C:3]1C=CC(C=NO)=[CH:5][CH:4]=1.[Cl:12][N:13]1[C:17](=[O:18])[CH2:16][CH2:15][C:14]1=O.O>CN(C)C=O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:16]([C:17]([NH:13][Cl:12])=[O:18])=[CH:15][CH:14]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 31398ChlorosuccinimideHCID 94712N-[(4-Methoxyphenyl)methylidene]hydroxylamine

Produkt 1

HCID 21579386N-Chloro-4-methoxybenzamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

Dissolved in 65 ml of dimethylformamide were 6.5 g (43 mmol) of 4 -methoxybenzaldoxime, followed by the gradual addition of 6.3 g (47 mmol) of N-chlorosuccinimide at room temperature. After the resultant mixture was stirred for 3 hours, 300 ml of water were added to the reaction mixture. The mixture thus formed was extracted with ethyl ether. The ether layer was washed with saturated saline and then dried over anhydrous magnesium sulfate. The solvent was distilled off, whereby 4-methoxybenzhydroxamic acid chloride was obtained.

Aufarbeitung

  1. customThe mixture thus formed
  2. extractionwas extracted with ethyl ether
  3. washThe ether layer was washed with saturated saline
  4. dry with materialdried over anhydrous magnesium sulfate
  5. distillationThe solvent was distilled off

Quellen und Nachweise

ORD-Eintrag
ord-aa38c33726504debb3a09f7882b2b56d
Quelldatensatz
uspto-grants-1997_02
Patentnummer
US05602160

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