Ammonia → 5-amino-3-methylsulfonylamino-1H-indazole
Reaktionsgleichung
[CH3:1][S:2]([NH:5][C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([N+:15]([O-])=O)[CH:13]=2)[NH:8][N:7]=1)(=[O:4])=[O:3].C(O)C.N>O>[NH2:15][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[NH:8][N:7]=[C:6]2[NH:5][S:2]([CH3:1])(=[O:4])=[O:3]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
5-Amino-3-methylsulfonylamino-1H-indazole can be obtained as described in Example 4 from 256 mg of 3-methylsulfonylamino-5-nitro-1H-indazole, 10 ml of ethanol, 2 g of ferrous sulfate, 3.2 ml of water and 2.4 ml of 32% aqueous ammonia. 0.1 g of 5-amino-3-methylsulfonylamino-1H-indazole is thus obtained in the form of an oil used as it is in the following step.
Quellen und Nachweise
- ORD-Eintrag
- ord-f321f5f43589499298e470735efc4ddf
- Quelldatensatz
- uspto-grants-2009_01
- Patentnummer
- US07473701B2
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