Methanesulfonyl chloride → 3-methylsulfonylamino-5-nitro-1H-indazole

HRID 1452860Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1452860
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[CH:9]=2)[NH:4][N:3]=1.[CH3:14][S:15](Cl)(=[O:17])=[O:16]>N1C=CC=CC=1>[CH3:14][S:15]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[CH:9]=2)[NH:4][N:3]=1)(=[O:17])=[O:16]

Komponenten

4

Edukt 2

HCID 31297Methanesulfonyl chlorideHCID 31366553-Amino-5-nitroindazole

Produkt 1

HCID 225672013-methylsulfonylamino-5-nitro-1H-indazoleAusbeute 84,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

3-Methylsulfonylamino-5-nitro-1H-indazole can be obtained as described in Example 2 from 0.7 g of 3-amino-5-nitro-1H-indazole, 23 ml of pyridine and 0.455 g of methylsulfonyl chloride. 0.85 g of 3-methylsulfonylamino-5-nitro-1H-indazole is thus obtained in the form of an orange powder used as it is in the following step.

Quellen und Nachweise

ORD-Eintrag
ord-258781a826894dd9831e0358f5a3dd02
Quelldatensatz
uspto-grants-2009_01
Patentnummer
US07473701B2

Notizen zur Reaktion

Wird geladen…