Isobutyl chloride → 2-Isopropyl-5-nitrobenzofuran
Reaktionsgleichung
[Br-].[OH:2][C:3]1[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][C:4]=1[CH2:5]P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:32](Cl)[CH:33]([CH3:35])[CH3:34]>>[CH:33]([C:35]1[O:2][C:3]2[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][C:4]=2[CH:5]=1)([CH3:34])[CH3:32]Komponenten
3
Versuchsvorschrift
Reaction of 2-hydroxy-5-nitrobenzyl triphenylphosphine bromide (prepared as described in Example 1(a) (40 g, 0.08 mol) and isobutyl chloride (10,6, 0.1. mol) was carried out with the method described in Example 1(b) to produce 19.7 g of 2-isopropyl-5-nitrobenzofuran.
Aufarbeitung
- customprepared
Quellen und Nachweise
- ORD-Eintrag
- ord-619f38cb936a4a90b63a1621d3d358db
- Quelldatensatz
- uspto-grants-1998_12
- Patentnummer
- US05854282
Notizen zur Reaktion
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