M-Cresol → HCID 178484371, Verbindung
Reaktionsgleichung
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([F:15])[CH:10]=1.[CH3:16][N:17]([CH3:20])[C:18]#[N:19].C1C(O)=CC=CC=1C>>[F:15][C:11]1[CH:10]=[C:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[NH:2][C:18]([N:17]([CH3:20])[CH3:16])=[NH:19])[CH:14]=[CH:13][CH:12]=1Komponenten
4
Versuchsvorschrift
A mixture of 2-amino-3'-fluorobiphenyl hydrochloride (3.6 g), N,N-dimethylcyanamide (1.7 g) and m-cresol (25 ml) was heated at 90°-95° C. for 8 hours to give N-(3'-fluoro-2-biphenylyl)-N',N'-dimethyl guanidine (m.p. 109°-110° C.) as a colourless solid which was recrystallised from hexane.
Aufarbeitung
- temperaturewas heated at 90°-95° C. for 8 hours