HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Lithium Hydroxide → 3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Lithium Hydroxide | HCID 3939 | — |
| Edukt | 3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester | HCID 66765236 | — |
| Lösungsmittel | MeOH tetrahydrofuran | HCID 21899815 | — |
| Produkt | 3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid | HCID 56840633 | — |
Reaktionsschritte
3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester (0.040 g, 0.086 mmol) was dissolved in THF:MeOH (1:1) then LiOH (1M aq.) was added and the reaction stirred at room temperature overnight. Acid-base extraction afforded the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09000025B2 |
| Quelldatensatz | uspto-grants-2015_04 |
| ORD ID | ord-16af161da1cf49d7bca79d8b1daf2841 |
| Quellennotiz | uspto-grants-2015_04 |