HRID1466773

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1cccc(Sc2c(C)n(Cc3ccccc3)c3cc(Br)ccc23)c1

HCID66765236

未命名化合物

PRODUCTS

生成物

结构：Cc1c(Sc2cccc(C(=O)O)c2)c2ccc(Br)cc2n1Cc1ccccc1

HCID56840633

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21899815

未命名化合物

PROCEDURE

实验过程

3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester (0.040 g, 0.086 mmol) was dissolved in THF:MeOH (1:1) then LiOH (1M aq.) was added and the reaction stirred at room temperature overnight. Acid-base extraction afforded the title compound.

WORKUP

后处理

extractionAcid-base extraction