Spiro(4.5)dec-6-ene-8-one → Spiro(4.5)decan-8-one

HRID 1478151

Reaktionsgleichung

Reaktionsgleichung von HRID 1478151
[CH2:1]1[C:5]2([CH2:10][CH2:9][C:8](=[O:11])[CH:7]=[CH:6]2)[CH2:4][CH2:3][CH2:2]1>C(O)C.[Pd]>[CH2:1]1[C:5]2([CH2:10][CH2:9][C:8](=[O:11])[CH2:7][CH2:6]2)[CH2:4][CH2:3][CH2:2]1

Komponenten

4

Edukt 1

HCID 139772Spiro(4.5)dec-6-ene-8-one

Produkt 1

HCID 14626805Spiro(4.5)decan-8-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of spiro[4.5]dec-6-en-8-one (442 mg, 2.94 mmol) in ethanol (15 mL) was flushed with nitrogen and treated with 10% Pd—C, 50% wet (Alfa Aesar, 38303) (313 mg, 2.94 mmol). The reaction mixture was stirred for 16 hours under an atmosphere of hydrogen and filtered through Celite®, rinsing with ethanol. The filtrate was concentrated under reduced pressure to afford the title compound;

Aufarbeitung

  1. filtrationfiltered through Celite®
  2. washrinsing with ethanol
  3. concentrationThe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-7214d5f0f6e94bf3880febeb25985d14
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09403810B2

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