Dimethylamine, hydrochloride → HCID 76280926, Verbindung
Reaktionsgleichung
[CH:1]1([C:4]2[C:5]([O:21][CH2:22][C:23]([F:26])([F:25])[F:24])=[CH:6][C:7]([C:10]([NH:12][CH:13]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:14]([OH:16])=O)=[O:11])=[N:8][CH:9]=2)[CH2:3][CH2:2]1.Cl.[CH3:28][NH:29][CH3:30]>>[CH:1]1([C:4]2[C:5]([O:21][CH2:22][C:23]([F:24])([F:25])[F:26])=[CH:6][C:7]([C:10]([NH:12][CH:13]([C:17]([CH3:19])([CH3:18])[CH3:20])[C:14]([N:29]([CH3:30])[CH3:28])=[O:16])=[O:11])=[N:8][CH:9]=2)[CH2:2][CH2:3]1Komponenten
3
Versuchsvorschrift
The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonyl]amino]-3,3-dimethyl-butanoic acid (Example 194b) and dimethylamine hydrochloride as starting materials and isolated (24 mg, 46%); MS (ESI, m/z): 402.6 (M+H+).
Aufarbeitung
- customisolated (24 mg, 46%)