Hydrazine hydrate (1:1) → HCID 178430911, Verbindung

HRID 1488169Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1488169
C(O/[CH:4]=[C:5](\[CH3:12])/[C:6](=O)[C:7]([F:10])([F:9])[F:8])C.O.[NH2:14][NH2:15]>CCO>[CH3:12][C:5]1[C:6]([C:7]([F:10])([F:9])[F:8])=[N:14][NH:15][CH:4]=1

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 10997657(3E)-4-ethoxy-1,1,1-trifluoro-3-methylbut-3-en-2-one2×

Produkt 1

HCID 178430911HCID 178430911, VerbindungAusbeute 93,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

Into a 100-mL round-bottom flask, was placed (E)-4-ethoxy-1,1,1-trifluoro-3-methylbut-3-en-2-one (compound 261.1, 2.6 g, 14.3 mmol) in EtOH (20 mL). Hydrazine hydrate (1.8 mL, 38 mmol) was added and the resulting solution was stirred for 2 h at 80° C. The reaction was concentrated under reduced pressure to obtain the title compound as a yellow oil (2 g, crude).

Aufarbeitung

  1. customInto a 100-mL round-bottom flask, was placed
  2. concentrationThe reaction was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-8ee4985915c64c7e9fd2fd372f022501
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09428502B2

Notizen zur Reaktion

Wird geladen…