Hydrazine hydrate (1:1) → HCID 90029563, Verbindung

HRID 1488174Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1488174
[CH3:1][CH:2]([C:5](=O)[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1)[CH:3]=O.O.[NH2:13][NH2:14]>C(O)C>[CH3:1][C:2]1[CH:3]=[N:13][NH:14][C:5]=1[CH:6]1[CH2:10][CH2:9][O:8][CH2:7]1

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 90021327HCID 90021327, Verbindung2×

Produkt 1

HCID 90029563HCID 90029563, VerbindungAusbeute 119,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

Into a 100-mL round-bottom flask, was placed a solution of 2-methyl-3-oxo-3-(tetrahydrofuran-3-yl)propanal (compound 263.3, 3.00 g, 19.2 mmol) in ethanol (25 mL). Hydrazine hydrate (1.16 mL, 24 mmol) was added and the resulting solution was stirred for 3 h at 80° C. The resulting mixture was concentrated under reduced pressure to obtain the title compound as a colorless oil (3.5 g, crude).

Aufarbeitung

  1. customInto a 100-mL round-bottom flask, was placed
  2. concentrationThe resulting mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-550f9aca6b634bdca46f268ea30b6693
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09428502B2

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