1-Methoxy-4-(methylthio)benzene → 2-(5-Methoxy-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Methoxy-4-(methylthio)benzene	HCID 15885	—
Reagenz	Bis(pinacolato)diborane	HCID 2733548	—
Reagenz	2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine	HCID 134956623	—
Katalysator	Bis(1,5-cyclooctadiene)dimethoxydiiridium	HCID 76001521	—
Lösungsmittel	P-Xylene	HCID 7809	—
Produkt	2-(5-Methoxy-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane	HCID 132510260	66%

Reaktionsbedingungen

Temperatur	55 °C

Reaktionsschritte

Ligand 3f: A mixture of ortho- and meta-borylated products (92 mg, 66% yield, ortho/meta + para = >20); ortho-borylated product 4c was obtained by further purification by GPC (70 mg, 50% yield), white solid (mp. 71-73 oC)

Herkunft & Nachweise

DOI	10.1002/anie.201610041
Quelldatensatz	Borylation dataset from Roche
ORD ID	ord-2aa42d9e8bac447fb49a48f178396241
Quellennotiz	Borylation dataset from Roche