Hydrochloric Acid → {2-[4-(Trifluoromethyl)phenyl]hydrazinylidene}acetic acid

HRID 1491787Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1491787
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:8]=[CH:7][C:6]([NH:9][NH2:10])=[CH:5][CH:4]=1.Cl.O.[C:15]([OH:19])(=[O:18])[CH:16]=O>O>[F:1][C:2]([F:11])([F:12])[C:3]1[CH:4]=[CH:5][C:6]([NH:9][N:10]=[CH:16][C:15]([OH:19])=[O:18])=[CH:7][CH:8]=1

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 1362004-(Trifluoromethyl)phenylhydrazineHCID 15620607Glyoxylic acid, monohydrate

Produkt 1

HCID 69587423{2-[4-(Trifluoromethyl)phenyl]hydrazinylidene}acetic acidAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To a mixture of 5.0 g of 4-(trifluoromethyl)phenylhydrazine (28.4 mmol), 31 ml of water and 3.1 ml of concentrated hydrochloric acid was added 2.9 g of glyoxylic acid-hydrate (31.4 mmol), and the mixture was stirred for one hour at room temperature. The precipitates thus separated out was collected by filtration, washed with water and dried over phosphorus pentoxide to give 6.26 g of 4-(trifluoromethyl)phenylhydrazonoacetic acid (95%) as a pale yellow powder.

Aufarbeitung

  1. customThe precipitates thus
  2. customseparated out
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. dry with materialdried over phosphorus pentoxide

Quellen und Nachweise

ORD-Eintrag
ord-dbe0084c260f4f5bbae3f3ddbe8acaae
Quelldatensatz
uspto-grants-1994_12
Patentnummer
US05371101

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