Reaktionsgleichung
[C@@H]1([N:9]2[CH:17]=[C:15]([CH3:16])[C:13](=[O:14])NC2=O)O[C@H](CO)[C@@H](O)C1.C1N(CCO)CCN(CCS(O)(=O)=O)C1.C1N=C(N)C2N=CN([C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H](N5C=C(C(N)=O)CC=C5)[C@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)C=2N=1.C1C=[N+]([C@@H]2O[C@H](COP(OP(OC[C@H]3O[C@@H](N4C5N=CN=C(N)C=5N=C4)[C@H](OP(O)(O)=O)[C@@H]3O)(O)=O)(O)=O)[C@@H](O)[C@H]2O)C=C(C(N)=O)C=1.C(C=C)=O.CCN(C(SSC(N(CC)CC)=S)=S)CC.C(=O)CC.[CH:149](=O)[C:150]1[CH:155]=[CH:154][CH:153]=[CH:152][CH:151]=1>>[CH2:155]([C:150]1[CH:149]=[CH:16][C:15]([CH:13]=[O:14])=[C:17]([NH2:9])[C:151]=1[CH2:152][CH3:153])[CH3:154]Komponenten
9
Versuchsvorschrift
Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal supplied by the Department of Pharmaceutical Development at our Institute. [3H]-Thymidine was purchased from New England Nuclear, Boston, Mass. Concanavalin A, horse serum, RPMI-1640 and HEPES were from Gibco, Grand Island, N.Y. NAD and NADP were purchased from Boehringer, Mannheim. Acrolein and disulfiram were obtained from Aldrich Chemical Co., Milwaukee, Wis. Propionaldehyde and benzaldehyde were from Eastman Kodak Chemical Co., Rochester, N.Y. Diethyl aminobenzaldehyde (DEAB) was kindly provided by Dr. John Hilton, Johns Hopkins School of Medicine, Baltimore, Md.
Aufarbeitung
- customMaterials: SDA was prepared by acid hydrolysis of the corresponding bioacetal
Quellen und Nachweise
- ORD-Eintrag
- ord-5424f1799aac4456a064308777a3601d
- Quelldatensatz
- uspto-grants-1994_12
- Patentnummer
- US05374658
Verknüpfte Notizen
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