Ethanol → N'-[1-(Pyridin-2-yl)ethylidene]benzohydrazide

HRID 1493686Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1493686
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:11]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=1)(=O)[CH3:12].C(O)C>O1CCOCC1>[N:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[C:11](=[N:10][NH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH3:12]

Komponenten

5

Edukt 3

HCID 702EthanolHCID 11955BenzoylhydrazineHCID 142862-Acetylpyridine

Produkt 1

HCID 1072163N'-[1-(Pyridin-2-yl)ethylidene]benzohydrazideAusbeute 64 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A mixture of 6.81 gm (0.05 mole) of benzhydrazide, 6.06 gm (0.05 mole) of 2-acetylpyridine and 100 ml of ethanol is stirred at reflux 2 hr. Then sufficient dioxane is added to the boiling mixture to furnish a solution. The hot solution is filtered. The filtrate is diluted to the cloud point with water, cooled to room temperature, and then chilled in the refrigerator. The product is collected and dried to yield 7.61 gm (64%) of the title compound having a melting point of 151.6° C.

Aufarbeitung

  1. temperatureat reflux 2 hr
  2. customto furnish a solution
  3. filtrationThe hot solution is filtered
  4. additionThe filtrate is diluted to the cloud point with water
  5. temperaturechilled in the refrigerator
  6. customThe product is collected
  7. customdried

Quellen und Nachweise

ORD-Eintrag
ord-74c2e0002ae14275a41098f9debcca1d
Quelldatensatz
uspto-grants-1991_06
Patentnummer
US05023334

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