Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one

Beteiligte Stoffe

Reaktionsschritte

Pyridinium p-toluenesulfonate (65 mg) was added to an ethanol solution (16 mL) of 4-benzyloxy-1-{4-[(2-tetrahydropyranyl)oxy]phenyl}-1H-pyridin-2-one (982 mg, 2.60 mmols) and refluxed for an hour. The reaction liquid was cooled to room temperature and the precipitate was recovered by filtration and washed with water and ethyl acetate to provide the title compound (746 mg, 98%).

Herkunft & Nachweise