反应详情

Pyridinium p-toluenesulfonate (65 mg) was added to an ethanol solution (16 mL) of 4-benzyloxy-1-{4-[(2-tetrahydropyranyl)oxy]phenyl}-1H-pyridin-2-one (982 mg, 2.60 mmols) and refluxed for an hour. The reaction liquid was cooled to room temperature and the precipitate was recovered by filtration and washed with water and ethyl acetate to provide the title compound (746 mg, 98%).

1. temperaturerefluxed for an hour
2. customThe reaction liquid
3. filtrationthe precipitate was recovered by filtration
4. washwashed with water and ethyl acetate