Cesium carbonate → Tert-butyl 3-(6-methoxy-5-(7-methylbenzo[d]thiazol-2-yl)-2-morpholino-1,6-dihydropyrimidin-4-ylamino)piperidine-1-carboxylate

Reaktionsgleichung

I[C:2]1[CH:7]([O:8][CH3:9])[NH:6][C:5]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[N:4][C:3]=1[NH:16][C@@H:17]1[CH2:22][CH2:21][CH2:20][N:19]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:18]1.[CH3:30][C:31]1[C:39]2[S:38][CH:37]=[N:36][C:35]=2[CH:34]=[CH:33][CH:32]=1.C(=O)([O-])[O-].[Cs+].[Cs+]>CN(C)C=O.[Pd].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.I[Cu]>[CH3:9][O:8][CH:7]1[NH:6][C:5]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[N:4][C:3]([NH:16][CH:17]2[CH2:22][CH2:21][CH2:20][N:19]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:18]2)=[C:2]1[C:37]1[S:38][C:39]2[C:31]([CH3:30])=[CH:32][CH:33]=[CH:34][C:35]=2[N:36]=1