Water → HCID 58320692, Verbindung

HRID 1515369Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1515369
[CH3:1][CH2:2][C:3]([C:5](Cl)=[O:6])=[O:4].C=[C:9]1[O:13][CH2:12]C[O:10]1.N1[CH:19]=[CH:18]C=CC=1.[OH2:20]>C(Cl)Cl>[O:13]1[CH2:12]/[C:1](=[CH:2]\[C:3](=[O:4])[C:5]([O:6][CH2:18][CH3:19])=[O:20])/[O:10][CH2:9]1

Komponenten

6

Edukt 4

HCID 962WaterHCID 1049PyridineHCID 11007880Butanoyl chloride, 2-oxo-HCID 117684952-Methylene-1,3-dioxolane

Produkt 1

HCID 58320692HCID 58320692, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
5 °C

Versuchsvorschrift

The solution of ethyloxalyl chloride (10.3 g, 75.5 mmol) in CH2Cl2 (10 mL) was added at 0° C. to the solution of methylene dioxolane (6.5 g, 75.5 mmol) and pyridine (6.3 g, 80 mmol) in CH2Cl (80 mL). The reaction mixture was stirred for 10 hours at 5° C. and diluted with 200 ml of water. The product was extracted with 200 ml of hexane, the solution of hexane was dried with MgSO4 and concentrated by evaporation. This gave 11.9 g (85%) of the product, b.p. 106-110° C./0.5 mmHg.

Aufarbeitung

  1. extractionThe product was extracted with 200 ml of hexane
  2. dry with materialthe solution of hexane was dried with MgSO4
  3. concentrationconcentrated by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-a5537c31416c4e8abd352e75baddf41d
Quelldatensatz
uspto-grants-2012_07
Patentnummer
US08222435B2

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