Thionyl Chloride → N-(2-chloroethyl)-N-methyl-octadecyl ammonium chloride

HRID 1525804Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1525804
S(Cl)([Cl:3])=O.O[CH2:6][CH2:7][N:8]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH3:9]>ClCCCl>[Cl-:3].[Cl:3][CH2:6][CH2:7][NH+:8]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH3:9]

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 13564486N-(2-hydroxyethyl)-N-methyl-octadecylamine

Produkt 1

HCID 86722748N-(2-chloroethyl)-N-methyl-octadecyl ammonium chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel2×

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Thionyl chloride (0.45 mL) was dissolved in 1,2-dichloroethane (3.0 mL). The solution of N-(2-hydroxyethyl)-N-methyl-octadecylamine (1.0 g) in 1,2-dichloroethane (7.0 mL) was added thereto at 0° C., followed by stirring at 50° C. for 30 minutes. The reaction solution was concentrated under reduced pressure and azeotrope was carried out with toluene twice to obtain the title compound (1.2 g) having the following physical property values.

Aufarbeitung

  1. customat 0° C.
  2. concentrationThe reaction solution was concentrated under reduced pressure and azeotrope

Quellen und Nachweise

ORD-Eintrag
ord-ea442a2ce6364d72b993fe7baaff4c19
Quelldatensatz
uspto-grants-2015_07
Patentnummer
US09085523B2

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