N-bromobutanimide → HCID 10755030, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4]1[C:8]([CH3:9])=[C:7]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[O:6][N:5]=1)[CH3:2].C1C(=O)N([Br:22])C(=O)C1>ClC(Cl)(Cl)Cl.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>[Br:22][CH2:9][C:8]1[C:4]([O:3][CH2:1][CH3:2])=[N:5][O:6][C:7]=1[C:10]([O:12][CH2:13][CH3:14])=[O:11]Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
Ethyl 3-Ethoxy-4-methylisoxazole-5-carboxylate (18 g, 91 mmol), NBS (17.5 g, 100 mmol), dibenzoyl peroxide (1 g, 4.1 mmol) in tetrachloromethane (500 mL) was boiled under reflux for 16 h. The mixture was cooled, filtered and concentrated in vacuo to afford the crude title compound (24.5 g, 97%).
Aufarbeitung
- temperatureunder reflux for 16 h
- temperatureThe mixture was cooled
- filtrationfiltered
- concentrationconcentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-e01f0c340c884ad8bf0ba4c54b52957e
- Quelldatensatz
- uspto-grants-2001_03
- Patentnummer
- US06200999B1
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