N,N-Dimethyl-1,3-propanediamine → HCID 22013769, Verbindung

HRID 1532657Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1532657
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH2:6].Cl[C:9]1[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][C:10]=1[N+:20]([O-:22])=[O:21]>C(OCC)(=O)C>[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH:6][C:9]1[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][C:10]=1[N+:20]([O-:22])=[O:21]

Komponenten

4

Edukt 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 1268247Ethyl 4-chloro-3-nitrobenzoate

Produkt 1

HCID 22013769HCID 22013769, VerbindungAusbeute 101,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Reaktionsbedingungen

Temperatur
125 °C

Versuchsvorschrift

N,N-Dimethy-1,3-propanediamine (1.41 g) was added to ethyl 4-chloro-3-nitrobenzoate (1.59 g) and stirred for 12 hours at 125° C. The reaction mixture, with ethyl acetate added thereto, was washed with 1N sodium hydroxide aqueous solution, water, and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (2.07 g) as brown oil.

Aufarbeitung

  1. washwas washed with 1N sodium hydroxide aqueous solution, water, and saturated brine successively
  2. dry with materialdried over sodium sulfate anhydride
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-1f6d9195e4494539b03d21d4b032ff02
Quelldatensatz
uspto-grants-2001_03
Patentnummer
US06204264B1

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